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Smith and Williams" Introduction to the Principles of Drug Design by H. John Smith

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Published by Butterworth-Heinemann .
Written in English

Subjects:

  • Pharmacology,
  • Medical / Nursing,
  • Design,
  • Drugs,
  • Structure-activity relationshi,
  • Structure-activity relationships,
  • Health/Fitness

Book details:

The Physical Object
FormatHardcover
Number of Pages333
ID Numbers
Open LibraryOL10545717M
ISBN 100723612110
ISBN 109780723612117

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This third edition provides an introduction to the principles of rational drug design. It demonstrates these principles using real examples, illustrating the discovery of "lead" compounds and their manipulation to produce non-toxic drug candidates.   Buy Smith and Williams' Introduction to the Principles of Drug Design and Action 4 by Smith, H. John, Williams, Hywel (ISBN: ) from Amazon's Book Store. Everyday low prices and free delivery on eligible orders.2/5(1). Smith and Williams' Introduction to the Principles of Drug Design and Action. DOI link for Smith and Williams' Introduction to the Principles of Drug Design and Action. Smith and Williams' Introduction to the Principles of Drug Design and Action bookAuthor: John C. Dearden, Kenneth C. James.   Introduction to the Principles of Drug Design provides a framework of fundamental drug design and principles into which drugs following on developments may be fitted. This book presents the rationales behind the design of Edition: 1.

Smith and Williams' Introduction to the Principles of Drug Design and Action Third edition Edited by H. John Smith Welsh School of Pharmacy University of Wales Cardiff, UK ap harwood academic publishers Australia • Canada • China • France • Germany India • Japan • Luxembourg • Malaysia The Netherlands • Russia • Singapore. The first part of the book covers general aspects, methods, and principles for drug design and discovery, and the second part covers specific targets and diseases. The text contains more than color figures and 24 tables for rapid assimilation. Each chapter includes references for 3/5(1). The Book Entitled, An Introduction To Drug Design Aims To Optimize The Discovery Of Drugs At A Low Cost And On Occasions To Change Their Pharmacokinetic And Pharmacodyanamic Properties. The Introductory Chapter Which Forms The Basis Of Drug Discovery Is Followed By The Present-Day Thinking Regarding The Best Approaches To Drug Discovery Are Considered. This lecture will serve as an introduction to the impact of drug structure and design on a molecule’s pharmaceutical properties (e.g. solubility and stability) and pharmacokinetics (absorption, distribution, metabolism and excretion) and ultimately on its’ pharmaceutical development into a final product.

  Smith and Williams' Introduction to the Principles of Drug Design and Action, Third Edition. The book also explores the interface between pharmaceutical technology and physiological principles in drug design, a field of increased importance to industry. Smith and Williams' Introduction to the Principles of Drug Design and Action. The Principles of Drug Design course aims to provide students with an understanding of the process of drug discovery and development from the identification of novel drug targets to the introduction of new drugs into clinical practice. It covers the basic principles of how new drugs are discovered with. Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient.